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Scientists find superbugs in Delhi drinking water

Kate Kelland Reuters 04/07/2011 19:07
Scientists find superbugs in Delhi drinking water - Asia - health - India


A gene that makes bugs highly resistant to almost all known antibiotics has been found in bacteria in water supplies in New Delhi used by local people for drinking, washing and cooking, scientists said on Thursday.



The NDM 1 gene, which creates what some experts describe as "super superbugs", has spread to germs that cause cholera and dysentery, and is circulating freely in other bacteria in the Indian city capital of 14 million people, the researchers said.

"The inhabitants of New Delhi are continually being exposed to multidrug-resistant and NDM 1-positive bacteria", said Mark Toleman of Britain's Cardiff University School of Medicine, who published the findings in a study on Thursday.

A "substantial number" of them are consuming such bacteria on a daily basis, he told a briefing in London. "We believe we have discovered a very significant underlying source of NDM 1 in the capital city of India," he said.

NDM 1, or New Delhi metallo-beta-lactamase 1, makes bacteria resistant to almost all antibiotics, including the most powerful class, called carbapenems.

It first emerged in India three years ago and has now spread across the world. It has been found in a wide variety of bugs, including familiar pathogens like Escherichia coli, or E. coli.

No new drugs are on the horizon for at least 5-6 years to tackle it and experts are concerned that only a few major drug companies, such as GlaxoSmithKline (GSK.L) and AstraZeneca (AZN.L), still have strong antibiotic development programmes.



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